Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease
Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly related to hereditary disorders and congenital heart malformations such as bicuspid aortic valve (BAV). Pregnancy is considered a hi...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2021
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| Sorozat: | Heart (British Cardiac Society)
107 No. 21 |
| Tárgyszavak: | |
| doi: | 10.1136/heartjnl-2020-318183 |
| mtmt: | 31967758 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/23282 |
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| 100 | 1 | |a Campens Laurence | |
| 245 | 1 | 0 | |a Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease |h [elektronikus dokumentum] / |c Campens Laurence |
| 260 | |c 2021 | ||
| 300 | |a 1704-1709 | ||
| 490 | 0 | |a Heart (British Cardiac Society) |v 107 No. 21 | |
| 520 | 3 | |a Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly related to hereditary disorders and congenital heart malformations such as bicuspid aortic valve (BAV). Pregnancy is considered a high risk period in women with underlying aortopathy.The ESC EORP Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective global registry that enrolled 5739 women with pre-existing cardiac disease. With this analysis, we aim to study the maternal and fetal outcome of pregnancy in women with thoracic aortic disease.Thoracic aortic disease was reported in 189 women (3.3%). Half of them were patients with Marfan syndrome (MFS), 26% had a BAV, 8% Turner syndrome, 2% vascular Ehlers-Danlos syndrome and 11% had no underlying genetic defect or associated congenital heart defect. Aortic dilatation was reported in 58% of patients and 6% had a history of aortic dissection. Four patients, of whom three were patients with MFS, had an acute aortic dissection (three type A and one type B aortic dissection) without maternal or fetal mortality. No complications occurred in women with a history of aortic dissection. There was no significant difference in median fetal birth weight if treated with a beta-blocker or not (2960 g (2358-3390 g) vs 3270 g (2750-3570 g), p value 0.25).This ancillary analysis provides the largest prospective data review on pregnancy risk for patients with thoracic aortic disease. Overall pregnancy outcomes in women with thoracic aortic disease followed according to current guidelines are good. | |
| 650 | 4 | |a Klinikai orvostan | |
| 700 | 0 | 1 | |a Baris Lucia |e aut |
| 700 | 0 | 1 | |a Scott Nandita S. |e aut |
| 700 | 0 | 2 | |a Kollaborációs szervezet: ROPAC investigators group |e aut |
| 700 | 0 | 2 | |a Temesvári A. |e aut |
| 700 | 0 | 2 | |a Bálint H. |e aut |
| 700 | 0 | 2 | |a Kőhalmi D. |e aut |
| 700 | 0 | 2 | |a Merkely B. |e aut |
| 700 | 0 | 2 | |a Liptai C. |e aut |
| 700 | 0 | 2 | |a Nemes Attila |e aut |
| 700 | 0 | 2 | |a Forster Tamás |e aut |
| 700 | 0 | 2 | |a Kalapos Anita |e aut |
| 700 | 0 | 2 | |a Berek K. |e aut |
| 700 | 0 | 2 | |a Havasi K. |e aut |
| 700 | 0 | 2 | |a Ambrus Nóra |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/23282/1/Campens2021.pdf |z Dokumentum-elérés |