Microwave-assisted, solvent-free synthesis of 1-(alpha- or beta-hydroxynaphthyl)-1,2,3,4-tetrahydroisoquinolines by the Mannich reaction
As a new extension of the Mannich reaction of naphthols, 1-(hydroxynaphthyl)-substituted 1,2,3,4-tetrahydroisoquinolines were synthesized by the nucleophilic addition of 1- or 2-naphthol to 3,4-dihydroisoquinolines under solvent-free conditions, using microwave irradiation. The additions to 3-methyl...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2006
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| Sorozat: | TETRAHEDRON LETTERS
47 No. 23 |
| Tárgyszavak: | |
| doi: | 10.1016/j.tetlet.2006.03.169 |
| mtmt: | 1012929 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/22669 |