Co-occurrence of thyroid and breast cancer is associated with an increased oncogenic SNP burden
Epidemiological evidence suggests that synchronous or metachronous presentation of breast and thyroid cancers exceeds that predicted by chance alone. The following potential explanations have been hypothesized: common environmental or hormonal factors, oncogenic effect of the treatment for the first...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2021
|
| Sorozat: | BMC CANCER
21 No. 1 |
| doi: | 10.1186/s12885-021-08377-4 |
| mtmt: | 32079355 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/21943 |
| Tartalmi kivonat: | Epidemiological evidence suggests that synchronous or metachronous presentation of breast and thyroid cancers exceeds that predicted by chance alone. The following potential explanations have been hypothesized: common environmental or hormonal factors, oncogenic effect of the treatment for the first cancer, closer follow-up of cancer survivors, shared underlying genetic risk factors. While some cases were found to be related to monogenic disorders with autosomal inheritance, the genetic background of most cases of co-occurring breast and thyroid cancer is thought to be polygenic. |
|---|---|
| Terjedelem/Fizikai jellemzők: | Terjedelem: 11-Azonosító: 706 |
| ISSN: | 1471-2407 |