Diversity-oriented Functionalization of Cyclodienes Through Selective Cycloaddition/Ring-opening/Cross-metathesis Protocols; Transformation of a Flatland into Three-dimensional Scaffolds With Stereo- and Regiocontrol
This article presents selective transformations of some readily available cyclodienes through simple chemical procedures into novel functionalized small-molecular entities. The syntheses hereby described involved selective cycloadditions, followed by ring-opening metathesis of the resulting beta-lac...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2020
|
| Sorozat: | CHEMICAL RECORD
20 No. 10 |
| doi: | 10.1002/tcr.202000070 |
| mtmt: | 31410814 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/20968 |
| Tartalmi kivonat: | This article presents selective transformations of some readily available cyclodienes through simple chemical procedures into novel functionalized small-molecular entities. The syntheses hereby described involved selective cycloadditions, followed by ring-opening metathesis of the resulting beta-lactam or isoxazoline derivatives and selective cross-metathesis by differentiation of the olefin bonds on the alkenylated heterocycles. The cross-metathesis transformations have been detailed, which were performed under various experimental conditions with the aim of exploring chemodiscrimination of the olefin bonds and delivering the corresponding functionalized beta-lactam or isoxazoline derivatives. |
|---|---|
| Terjedelem/Fizikai jellemzők: | 1129-1141 |
| ISSN: | 1527-8999 |