Thromboticus esemenyek es az IPSET thrombosiskockazat-becslo pontrendszer jelentosege essentialis thrombocytaemiaban
INTRODUCTION: Thrombo-haemorrhagic complications contribute to both morbidity and mortality in patients with essential thrombocythaemia. AIM: The aim of the authors was to estimate the incidence of thrombotic events and to examine the clinical utility of IPSET thrombosis risk evaluation score agains...
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| Dokumentumtípus: | Cikk |
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2015
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| Sorozat: | ORVOSI HETILAP
156 No. 14 |
| doi: | 10.1556/OH.2015.30117 |
| mtmt: | 2891581 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/16342 |
| Tartalmi kivonat: | INTRODUCTION: Thrombo-haemorrhagic complications contribute to both morbidity and mortality in patients with essential thrombocythaemia. AIM: The aim of the authors was to estimate the incidence of thrombotic events and to examine the clinical utility of IPSET thrombosis risk evaluation score against conventional two-categorical (low and high) risk assessment. METHOD: A retrospective analysis was carried out on 155 patients with essential thrombocythaemia (106 females; median age, 61 years) in a period between 1999 and 2014. RESULTS: The analysis revealed 55 (35.5%) major thrombotic events before and 25 (16.1%) major thrombotic complications after establishment of the haematologic diagnosis. Significant differences were observed in thrombosis-free survival between the different IPSET groups (p = 0.002). CONCLUSIONS: The IPSET model was first examined in this cohort of patients with essential thrombocythaemia diagnosed in a single Hungarian haematologic centre. The results suggest that this score may provide more information than the conventional thrombosis risk assessment. Orv. Hetil., 2015, 156(14), 558-563. |
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| Terjedelem/Fizikai jellemzők: | 558-563 |
| ISSN: | 0030-6002 |