Preexisting Diabetes Elevates Risk of Local and Systemic Complications in Acute Pancreatitis Systematic Review and Meta-analysis. /

Preexisting Diabetes Elevates Risk of Local and Systemic Complications in Acute Pancreatitis Systematic Review and Meta-analysis. /

The prevalence of diabetes mellitus (DM) and acute pancreatitis (AP) increases continuously, therefore, to understand the effects of preexisting diabetes on AP is crucially needed. Here, we performed a systematic review and meta-analysis in which AP patients including DM and non-DM groups were sorte...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Mikó Alexandra
Borbásné Farkas Kornélia
Garami András
Szabó Imre
Vincze Áron
Veres Gábor
Bajor Judit
Alizadeh Hussain
Rakonczay Zoltán, ifj
Vigh Éva
Márta Katalin
Hegyi Péter
Czakó László
Dokumentumtípus: Cikk
Megjelent: 2018
Sorozat:PANCREAS 47 No. 8
doi:10.1097/MPA.0000000000001122

mtmt:3407191
Online Access:http://publicatio.bibl.u-szeged.hu/15413
Leíró adatok
Tartalmi kivonat:The prevalence of diabetes mellitus (DM) and acute pancreatitis (AP) increases continuously, therefore, to understand the effects of preexisting diabetes on AP is crucially needed. Here, we performed a systematic review and meta-analysis in which AP patients including DM and non-DM groups were sorted. Several outcome parameters were analyzed, and the odds ratio (OR) and standardized mean difference with 95% confidence intervals (CIs) were calculated.We found 1417 articles, of which 9 articles involving 354,880 patients were analyzed. More complications were seen in diabetic patients than in non-DM patients (OR, 1.553 [95% CI, 1.266-1.904]; P < 0.001). Intensive care unit admission (OR, 1.799 [95% CI, 1.442-2.243]; P < 0.001) and renal failure (OR, 1.585 [95% CI, 1.278-1.966]; P < 0.001) were more frequent in DM patients. There was a tendency of higher mortality and local complications (OR, 1.276 [95% CI, 0.991-1.643]; P = 0.059; and OR, 1.267 [95% CI, 0.964-1.659]; P = 0.090, respectively) in preexisting DM. Length of hospitalization was longer in DM patients (standardized mean difference, 0.217 [95% CI, 0.075-0.360]; P = 0.003). Preexisting DM negatively influences the outcome of AP and increases the risk of renal failure, local complications, and mortality.
Terjedelem/Fizikai jellemzők:917-923
ISSN:0885-3177

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