Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer
A series of novel mimetic peptides were designed, synthesised and biologically evaluated as inhibitors of Aβ42 aggregation. One of the synthesised peptidic compounds, termed compound 7 modulated Aβ42 aggregation as demonstrated by thioflavin T fluorescence, acting also as an inhibitor of the cytotox...
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| Main Authors: | |
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| Format: | Article |
| Published: |
2018
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| Series: | BIOORGANIC CHEMISTRY
81 |
| doi: | 10.1016/j.bioorg.2018.08.018 |
| mtmt: | 3405755 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/14901 |