Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer
A series of novel mimetic peptides were designed, synthesised and biologically evaluated as inhibitors of Aβ42 aggregation. One of the synthesised peptidic compounds, termed compound 7 modulated Aβ42 aggregation as demonstrated by thioflavin T fluorescence, acting also as an inhibitor of the cytotox...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2018
|
| Sorozat: | BIOORGANIC CHEMISTRY
81 |
| doi: | 10.1016/j.bioorg.2018.08.018 |
| mtmt: | 3405755 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/14901 |