One-pot synthesis of diverse N,N '-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines

A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Demjén András
Angyal Anikó
Wölfling János
Puskás László
Kanizsai Iván
Dokumentumtípus: Cikk
Megjelent: 2018
Sorozat:ORGANIC & BIOMOLECULAR CHEMISTRY 16 No. 12
doi:10.1039/c7ob03109b

mtmt:3389413
Online Access:http://publicatio.bibl.u-szeged.hu/14519
Leíró adatok
Tartalmi kivonat:A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol also features wide substrate scope and mild conditions.
Terjedelem/Fizikai jellemzők:2143-2149
ISSN:1477-0520