One-pot synthesis of diverse N,N '-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines
A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol...
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Dokumentumtípus: | Cikk |
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2018
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Sorozat: | ORGANIC & BIOMOLECULAR CHEMISTRY
16 No. 12 |
doi: | 10.1039/c7ob03109b |
mtmt: | 3389413 |
Online Access: | http://publicatio.bibl.u-szeged.hu/14519 |
Tartalmi kivonat: | A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol also features wide substrate scope and mild conditions. |
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Terjedelem/Fizikai jellemzők: | 2143-2149 |
ISSN: | 1477-0520 |