Obstetric and neonatal risk of pregnancies after assisted reproductive technology a matched control study /

Background. The aim of the study was to evaluate the obstetric and neonatal outcome of pregnancies after assisted reproduction technology (ART) in comparison with matched controls from spontaneous pregnancies. Methods. A total of 12 920 deliveries at the Department of Obstetrics and Gynecology, Univ...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kozinszky Zoltán
Zádori János
Orvos Hajnalka
Jancsó Gáborné Katona Márta
Pál Attila
Kovács László
Dokumentumtípus: Cikk
Megjelent: John Wiley and Sons, Inc. 2003
Sorozat:ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA 82 No. 9
doi:10.1034/j.1600-0412.2003.00225.x

mtmt:1388243
Online Access:http://publicatio.bibl.u-szeged.hu/12961
Leíró adatok
Tartalmi kivonat:Background. The aim of the study was to evaluate the obstetric and neonatal outcome of pregnancies after assisted reproduction technology (ART) in comparison with matched controls from spontaneous pregnancies. Methods. A total of 12 920 deliveries at the Department of Obstetrics and Gynecology, University of Szeged, from 1 January 1995 to 31 December 2001 were subjected to retrospective analysis. Two hundred and eighty-four singleton, 75 twin and 17 triplet pregnancies after ovulation induction (n = 114; 30.3%), intrauterine insemination (n = 33; 8.8%) and in vitro fertilization (n = 229; 60.9%) were evaluated. The pregnancy outcome of the singleton and twin pregnancies was compared with that for controls matched with regard to age, gravidity and parity and previous obstetric outcome after spontaneous pregnancies. Results. Twenty-four percent of the assisted reproductive pregnancies were multiple pregnancies. The incidences of singleton intrauterine growth retardation (IUGR) and preterm birth were reasonably similar to those among the controls (IUGR: 6.3% vs. 4.2%; preterm births: 13.0% vs. 9.9%, for the cases and the controls, respectively). As compared with the controls, there was an increased incidence of cesarean section among the singleton (41.2% vs. 34.5%, p = 0.12; OR 1.33; 95% CI 0.95-1.87) and twin assisted reproduction pregnancies (66.7% vs. 60.0%), but without significant differences. Conclusions. Increased obstetric risk could be observed concerning threatened preterm delivery and cesarean section rate in the study group. The perinatal outcome of singleton and twin pregnancies following assisted reproductive techniques is comparable with that of spontaneously conceived, matched pregnancies.
Terjedelem/Fizikai jellemzők:850-856
ISSN:0001-6349