Evaluation of oxidative stress markers after vaginal delivery or Caesarean section
Background: The effects of vaginal delivery (VD) and of cesarean section (CS) on the markers of oxidative stress were investigated. Materials and Methods: Umbilical blood samples were analyzed from 74 full-term neonates, 46 born via VD, 28 via elective CS. The level of lipid peroxidation (LP), prote...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
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2007
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| Sorozat: | IN VIVO
21 No. 4 |
| mtmt: | 1388236 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/12894 |
| Tartalmi kivonat: | Background: The effects of vaginal delivery (VD) and of cesarean section (CS) on the markers of oxidative stress were investigated. Materials and Methods: Umbilical blood samples were analyzed from 74 full-term neonates, 46 born via VD, 28 via elective CS. The level of lipid peroxidation (LP), protein and DNA damage and the antioxidant status were compared. Results: Differences between CS and VD groups were generally non-significant for oxidative markers, except for the GSH concentrations (VD: 4.18 vs. CS: 2.77 mu M/mg protein x 10(-3); p<0.05). LP was significantly higher in the CS group (0.078 vs. 0.042 nM MDA/mg protein; p < 0.05). The level of carbonyl proteins was high in the VD group and significantly lower in the elective CS group (9.5 vs. 8.1 mMlmg protein x 10(-4); p<0.05). We found 0.78% more strand breaks in elective CS group than in VD group. Conclusion: CS does not have an advantage over VD with respect to oxidative stress. |
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| Terjedelem/Fizikai jellemzők: | 703-706 |
| ISSN: | 0258-851X |