A genome-wide screen for association in Hungarian multiple sclerosis
Although the pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of genetic factors. We report on a genome-wide screen for disease association in the Hungarian population using 5532 microsatellite markers. These markers were typed in DN...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2003
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| Sorozat: | JOURNAL OF NEUROIMMUNOLOGY
143 No. 1-2 |
| doi: | 10.1016/j.jneuroim.2003.08.017 |
| mtmt: | 247816 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/10270 |
| Tartalmi kivonat: | Although the pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of genetic factors. We report on a genome-wide screen for disease association in the Hungarian population using 5532 microsatellite markers. These markers were typed in DNA pools that consisted of 88 MS patients (cases), and 128 unrelated controls. Based on a stringent selection criterion, we obtained 33 markers suggesting association with the disease. (C) 2003 Elsevier B.V. All rights reserved. |
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| Terjedelem/Fizikai jellemzők: | 84-87 |
| ISSN: | 0165-5728 |