Identification and characterization of sialylated glycolipids in TLR2D knockout gene
Gangliosides, complex glycosphingolipids essential for the central nervous system, play crucial roles in cellular processes such as cell adhesion, signal transduction, and cell-to-cell communication. Alterations in ganglioside composition are associated with various neurological disorders, underscor...
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| Dokumentumtípus: | Könyv része |
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University of Szeged
Szeged
2024
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
30 |
| Kulcsszavak: | Molekuláris biológia, Immunológia - kutatás, Lipidomika, Genetika |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/85678 |
| Tartalmi kivonat: | Gangliosides, complex glycosphingolipids essential for the central nervous system, play crucial roles in cellular processes such as cell adhesion, signal transduction, and cell-to-cell communication. Alterations in ganglioside composition are associated with various neurological disorders, underscoring the importance of studying these molecules for a better understanding of neural function and pathology. This study characterized the ganglioside profiles in mouse brain tissues from four distinct groups: wild-type females (WF), knockout females (KF) with the TLR2D gene inhibited, wild-type males (WM), and knockout males (KM). |
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| Terjedelem/Fizikai jellemzők: | 98-99 |
| ISBN: | 978-963-688-009-5 |