Application of a 3D-printed, high efficiency sample introduction system for single cell ICP-MS analysis
In this study, the application of an alternative, 3D-printed sample introduction system (SIS) is presented for single cell ICP-MS analysis. The SIS utilized in the experiments was designed by our group with the purpose to enhance single particle detection capabilities. It is able to provide higher t...
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| Dokumentumtípus: | Könyv része |
| Megjelent: |
University of Szeged
Szeged
2023
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
29 |
| Kulcsszavak: | Analitikai kémia - számítógép alkalmazása |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/82412 |
| Tartalmi kivonat: | In this study, the application of an alternative, 3D-printed sample introduction system (SIS) is presented for single cell ICP-MS analysis. The SIS utilized in the experiments was designed by our group with the purpose to enhance single particle detection capabilities. It is able to provide higher transport efficiencies, increased sensitivity, lower background signals and a wider range of detectable particle size in single particle ICP-MS (spICP-MS) analysis compared to the standard SIS. Capitalizing on these features, two single cell ICP-MS (scICP-MS) experiments were done, using single cellular algae (Chlorella) and human endothelial cell suspensions, thereby demonstrating the SIS’s ability to facilitate cell biology related studies such as determining the elemental composition/metal uptake of a single cell or monitoring its cell-tocell variation in cell cultures. |
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| Terjedelem/Fizikai jellemzők: | 172-175 |
| ISBN: | 978-963-306-963-9 |