Novel platinum complexes with schiff bases and α-Dioximes, their physico-chemical and biological study

In our research project we prepared the following platinum(II) complexes with Schiff bases and -dioximes, such as [Pt(ketone)2A(L2)], (ketone: 2-heptanone, 2-octanone, 3-octanone; A: hydrazine, phenylhydrazine, o-phenylene-diamine; L: 1-naphthylamine, 2-aminopyrimidine, 2-methylimidazole, 2-amino-4...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Várhelyi Csaba
Szalay Roland
Pokol György
Madarász János
Huszthy Péter
Simon-Várhelyi Melinda
Tötös Róbert
Mereu Raluca-Anca
Papp Judit
Mihály Judith
Testületi szerző: 29th International Symposium on Analytical and Environmental Problems
Dokumentumtípus: Könyv része
Megjelent: University of Szeged Szeged 2023
Sorozat:Proceedings of the International Symposium on Analytical and Environmental Problems 29
Kulcsszavak:Környezetkémia
Tárgyszavak:
Online Access:http://acta.bibl.u-szeged.hu/82362
Leíró adatok
Tartalmi kivonat:In our research project we prepared the following platinum(II) complexes with Schiff bases and -dioximes, such as [Pt(ketone)2A(L2)], (ketone: 2-heptanone, 2-octanone, 3-octanone; A: hydrazine, phenylhydrazine, o-phenylene-diamine; L: 1-naphthylamine, 2-aminopyrimidine, 2-methylimidazole, 2-amino-4-methylpyridine) and [Pt(DioxH)2L2], (DioxH2: methyl-phenyl-dioxime, butyl-methyl-dioxime; L: 1-naphthylamine, 2-methylimidazole, 2-amino-4-methylpyridine, lepidine, 2-methylpyridine, m-toluidine, dicyclohexylamine, 4-isopropylamine, cyclohexylamine), by the reaction of PtCl2 in suitable solvent. After a short bibliographical survey, involving the classification and evolution of platinum complexes with possible applications, we analyzed their physico-chemical properties using FTIR, Raman, NMR, UV-VIS spectroscopy, powder X-ray diffraction (XRD), mass spectrometry, thermal analysis (TG, DTG, DTA) and SEM. We also studied the antibacterial effect of complexes on different strains of bacteria. This class of compounds has relevance in biochemistry, some of them are antibacterial agents and potential anti-tumor drugs.
Terjedelem/Fizikai jellemzők:50-55
ISBN:978-963-306-963-9