Investigation of the transformation of 5-fluorouracil cytostatics by UV and VUV photolysis
In this work, UV (254 nm), UV/VUV185 nm, and VUV172 nm photolysis of 5-fluorouracil (5- FLU), a cytostatic drug were investigated. For the water treatments three type of lightsources were applied: a low-pressure mercury vapour lamps emitting only 254 nm UV light, an other low-pressure mercury vapour...
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| Dokumentumtípus: | Könyv része |
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2020
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
26 |
| Kulcsszavak: | Analitikai kémia |
| Tárgyszavak: | |
| Online Access: | http://acta.bibl.u-szeged.hu/74043 |
| Tartalmi kivonat: | In this work, UV (254 nm), UV/VUV185 nm, and VUV172 nm photolysis of 5-fluorouracil (5- FLU), a cytostatic drug were investigated. For the water treatments three type of lightsources were applied: a low-pressure mercury vapour lamps emitting only 254 nm UV light, an other low-pressure mercury vapour lamps emitting both 254 nm UV and 185 nm VUV light, and a Xe excimer light source emitting 172 nm VUV photons. In parallel, with the transformation of 5-FLU, H2O2 formation was detected and measured. During UV/VUV185 nm photolysis, the formation of H2O2 follows a maximum curve, while in the case of UV photolysis, it shows a saturation curve. Its concentration reached higher value in the case of UV/VUV185 nm than in UV radiation. To enhance the efficiency of the reactors, we used air, O2 and N2 gases and assessed their effect to the photolysis of 5-FLU to see wich parameters are the most suitable for transforming it. |
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| Terjedelem/Fizikai jellemzők: | 379-383 |
| ISBN: | 978-963-306-771-0 |