New way to green biological assays fluorescent steroids replace radioisotopes
Novel BODIPY–estrone and BODIPY–estradiol conjugates have been synthesized via Cu(I)- catalyzed azide-alkyne click (CuAAC) and/or Sonogashira reactions by selecting position C3-O for labeling. The steroidal azides and/or bromides were reacted with BODIPY-based fluorescent dye bearing alkyne function...
Elmentve itt :
| Szerzők: | |
|---|---|
| Testületi szerző: | |
| Dokumentumtípus: | Könyv része |
| Megjelent: |
2019
|
| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
|
| Kulcsszavak: | Szerves kémia |
| Online Access: | http://acta.bibl.u-szeged.hu/64901 |
| Tartalmi kivonat: | Novel BODIPY–estrone and BODIPY–estradiol conjugates have been synthesized via Cu(I)- catalyzed azide-alkyne click (CuAAC) and/or Sonogashira reactions by selecting position C3-O for labeling. The steroidal azides and/or bromides were reacted with BODIPY-based fluorescent dye bearing alkyne function. The new fluorescent estrone conjugates might replace radiolabeled compounds in certain biochemical assays. |
|---|---|
| Terjedelem/Fizikai jellemzők: | 437-438 |
| ISBN: | 978-963-306-702-4 |