A green, fluorescent labeling of estrogens
Novel 2- or 3-labeled 13β- -estrone derivatives were synthesized via Cu(I)-catalyzed azide-alkyne click reaction (CuAAC). The steroidal alkynes or azides were reacted with the appropriate BODIPY-based fluorenscent dyes bearing the complementary functions. The newly synthesized fluorescent estrone de...
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Dokumentumtípus: | Könyv része |
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2018
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Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
24 |
Kulcsszavak: | Szerves kémia |
Online Access: | http://acta.bibl.u-szeged.hu/56383 |
Tartalmi kivonat: | Novel 2- or 3-labeled 13β- -estrone derivatives were synthesized via Cu(I)-catalyzed azide-alkyne click reaction (CuAAC). The steroidal alkynes or azides were reacted with the appropriate BODIPY-based fluorenscent dyes bearing the complementary functions. The newly synthesized fluorescent estrone derivatives may serve as good candidates for the development of “green” biological assays. |
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Terjedelem/Fizikai jellemzők: | 406-407 |
ISBN: | 978-963-306-623-2 |