Novel latonduine derived proligands and their copper(II) complexes show cytotoxicity in the nanomolar range in human colon adenocarcinoma cells and in vitro cancer selectivity

Bacher Felix, Wittmann Christopher, Nové Márta, Spengler Gabriella, Marć Małgorzata Anna, Enyedy Éva Anna, Darvasiova Denisa, Rapta Peter, Reiner Thomas, Arion Vladimir B.
2019

Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity /

Stepanenko Iryna, Babak Maria V., Spengler Gabriella, Hammerstad Marta, Popovic-Bijelic Ana, Shova Sergiu, Büchel Gabriel E., Darvasiova Denisa, Rapta Peter, Arion Vladimir B.
2021

Copper(II) thiosemicarbazone complexes induce marked ROS accumulation and promote nrf2-mediated antioxidant response in highly resistant breast cancer cells

Sirbu Angela, Palamarciuc Oleg, Babak Maria V., Lim Jia Min, Ohui Kateryna, Enyedy Éva Anna, Shova Sergiu, Darvasiova Denisa, Rapta Peter, Ang Wee Han, Arion Vladimir B.
2017

Investigation of the cytotoxic potential of methyl imidazole-derived thiosemicarbazones and their copper(II) complexes with dichloroacetate as a co-ligand

Palamarciuc Oleg, Milunović Miljan N. M., Sirbu Angela, Stratulat Elena, Pui Aurel, Gligorijevic Nevenka, Radulovic Sinisa, Kozisek Jozef, Darvasiova Denisa, Rapta Peter, Enyedy Éva Anna, Novitchi Ghenadie, Shova Sergiu, Arion Vladimir B.
2019

Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

Ohui Kateryna, Stepanenko Iryna, Besleaga Iuliana, Babak Maria V., Stafi Radu, Darvasiova Denisa, Giester Gerald, Pósa Vivien, Enyedy Éva Anna, Végh Dániel, Rapta Péter, Ang Wee Han, Popović-Bijelić Ana, Arion Vladimir B.
2020

Triapine Analogues and Their Copper(II) Complexes Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition /

Besleaga Iuliana, Stepanenko Iryna, Petrasheuskaya Tatsiana, Darvasiova Denisa, Breza Martin, Hammerstad Marta, Marć Małgorzata A., Prado-Roller Alexander, Spengler Gabriella, Popovic-Bijelic Ana, Enyedy Éva Anna, Rapta Peter, Shutalev Anatoly D., Arion Vladimir B.
2021

New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids Insights into the Anticancer and Antibacterial Mode of Action /

Ohui Kateryna, Afanasenko Eleonora, Bacher Felix, Ting Rachel Lim Xue, Zafar Ayesha, Blanco-Cabra Nuria, Torrents Eduard, Dömötör Orsolya, May Nóra Veronika, Darvasiova Denisa, Enyedy Éva Anna, Popovic-Bijelic Ana, Reynisson Johannes, Rapta Peter, Babak Maria V., Pastorin Giorgia, Arion Vladimir B.
2019

Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubu...

Milunovic Miljan N. M., Ohui Katerina, Besleaga Iuliana, Petrasheuskaya Tatsiana V., Dömötör Orsolya, Enyedy Éva Anna, Darvasiova Denisa, Rapta Peter, Barbieriková Zuzana, Vegh Daniel, Tóth Szilárd, Tóth Judit, Kucsma Nóra, Szakács Gergely, Popović-Bijelić Ana, Zafar Ayesha, Reynisson Jóhannes, Shutalev Anatoly D., Bai Ruoli, Hamel Ernest, Arion Vladimir B.
2024