Pharmacogenetics in advanced Parkinson's disease

Parkinson's disease (PD) is a progressive neurodegenerative disorder with a wide variety of symptoms and evolution. In addition, the response to antiparkinsonian medication is not predictable, especially for those patients with advanced PD. Pharmacogenetics and pharmacogenomics may help to deci...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kulisevsky Jaime
García-Ruíz Pedro
Outeiro Tiago Fleming
Gurevich Tanya
Klivényi Péter
Van Laar Teus
Milanov Ivan
Pirker Walter
Popescu Bogdan O
Toft Mathias
Szász József Attila
Dokumentumtípus: Cikk
Megjelent: 2025
Sorozat:JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION 132 No. 11
Tárgyszavak:
doi:10.1007/s00702-025-03057-0

mtmt:36435422
Online Access:http://publicatio.bibl.u-szeged.hu/38538
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520 3 |a Parkinson's disease (PD) is a progressive neurodegenerative disorder with a wide variety of symptoms and evolution. In addition, the response to antiparkinsonian medication is not predictable, especially for those patients with advanced PD. Pharmacogenetics and pharmacogenomics may help to decide the best available treatment based on the genetic background of the patients. This approach has been already used in Oncology leading to personalized pharmacology. In this article, we review and comment the updated information regarding pharmacogenetics and pharmacogenomics applied to PD. 
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700 0 2 |a Outeiro Tiago Fleming  |e aut 
700 0 2 |a Gurevich Tanya  |e aut 
700 0 2 |a Klivényi Péter  |e aut 
700 0 2 |a Van Laar Teus  |e aut 
700 0 2 |a Milanov Ivan  |e aut 
700 0 2 |a Pirker Walter  |e aut 
700 0 2 |a Popescu Bogdan O  |e aut 
700 0 2 |a Toft Mathias  |e aut 
700 0 2 |a Szász József Attila  |e aut 
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