Attentional modulation of perceptual organisation in schizophrenia

INTRODUCTION: Previous studies indicated impaired perceptual organisation in schizophrenia. This study investigated lateral connection and attentional modulation in early visual cortex of schizophrenia patients. METHODS: Contrast threshold was measured for a central Gabor patch, flanked with orthogo...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kéri Szabolcs
Kelemen Oguz
Benedek György
Dokumentumtípus: Cikk
Megjelent: 2009
Sorozat:COGNITIVE NEUROPSYCHOLOGY 14 No. 2
Tárgyszavak:
doi:10.1080/13546800902757936

mtmt:1340882
Online Access:http://publicatio.bibl.u-szeged.hu/37823
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520 3 |a INTRODUCTION: Previous studies indicated impaired perceptual organisation in schizophrenia. This study investigated lateral connection and attentional modulation in early visual cortex of schizophrenia patients. METHODS: Contrast threshold was measured for a central Gabor patch, flanked with orthogonal and collinear Gabor patches. In the attended condition, participants performed a concurrent vernier task by determining the spatial offset of the flankers. RESULTS: The controls (n=25) had lower contrast thresholds in the collinear condition than in the orthogonal condition, whereas the schizophrenia patients (n=43) did not benefit from the presence of collinear flankers. This deficit was not ameliorated by attentional modulation. Antipsychotic medication did not affect the performance. CONCLUSIONS: These results suggest that lateral connections are impaired in early visual cortex of schizophrenia patients. This deficit cannot be restored by top-down attentional modulation of target-flanker interactions. 
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700 0 1 |a Kelemen Oguz  |e aut 
700 0 1 |a Benedek György  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/37823/1/134088258.2009perceptualisorganizacio.pdf  |z Dokumentum-elérés