The Protein Encoded by The Gene Proliferation Disrupter (prod) is Associated With The Telomeric Retrotransposon Array in Drosophila Melanogaster
We report in this paper that the pentoxyresorufin-O-dealkylase (PROD) protein, encoded by the gene proliferation disrupter (prod), is associated with the telomeric chromatin in Drosophila melanogaster. It binds to a region just upstream of the promoter of the telomere-specific retrotransposon HeT-A,...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2007
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| Sorozat: | CHROMOSOMA
116 No. 2 |
| Tárgyszavak: | |
| doi: | 10.1007/s00412-006-0090-4 |
| mtmt: | 1915168 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/34310 |
| LEADER | 01471nab a2200253 i 4500 | ||
|---|---|---|---|
| 001 | publ34310 | ||
| 005 | 20240725113008.0 | ||
| 008 | 240725s2007 hu o 000 eng d | ||
| 022 | |a 0009-5915 | ||
| 024 | 7 | |a 10.1007/s00412-006-0090-4 |2 doi | |
| 024 | 7 | |a 1915168 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a eng | ||
| 100 | 1 | |a Török Tibor | |
| 245 | 1 | 4 | |a The Protein Encoded by The Gene Proliferation Disrupter (prod) is Associated With The Telomeric Retrotransposon Array in Drosophila Melanogaster |h [elektronikus dokumentum] / |c Török Tibor |
| 260 | |c 2007 | ||
| 300 | |a 185-195 | ||
| 490 | 0 | |a CHROMOSOMA |v 116 No. 2 | |
| 520 | 3 | |a We report in this paper that the pentoxyresorufin-O-dealkylase (PROD) protein, encoded by the gene proliferation disrupter (prod), is associated with the telomeric chromatin in Drosophila melanogaster. It binds to a region just upstream of the promoter of the telomere-specific retrotransposon HeT-A, which is located in the long 3'untranslated region of the element near its oligo(A) tail. Reduction of PROD in prod heterozygote flies results in elevated levels of HeT-A RNA in the ovaries, suggesting that PROD functions as a repressor of HeT-A transcriptional activity at the telomeres. | |
| 650 | 4 | |a Biológiai tudományok | |
| 700 | 0 | 1 | |a Benitez C |e aut |
| 700 | 0 | 1 | |a Takács Sándor |e aut |
| 700 | 0 | 1 | |a Biessmann H |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/34310/1/torok_et_al_2007.pdf |z Dokumentum-elérés |