Synthesis of Analogues of Thyrotropin-Releasing Hormone
The synthesis of ten new thyrotropin-releasing hormone analogues (15-24) which contain uncoded amino acids (L- and D-homoleucine, L- and D-homophenylalanine, L-homoproline and 6-ketopipecolic acid) is described here. The peptide bond formation was achieved in solution phase using pentafluorophenyl e...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
1994
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| Sorozat: | JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG
336 No. 6 |
| Tárgyszavak: | |
| doi: | 10.1002/prac.19943360609 |
| mtmt: | 1880328 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/31990 |
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| 024 | 7 | |a 10.1002/prac.19943360609 |2 doi | |
| 024 | 7 | |a 1880328 |2 mtmt | |
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| 245 | 1 | 0 | |a Synthesis of Analogues of Thyrotropin-Releasing Hormone |h [elektronikus dokumentum] / |c Somlai Csaba |
| 260 | |c 1994 | ||
| 300 | |a 525-529 | ||
| 490 | 0 | |a JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG |v 336 No. 6 | |
| 520 | 3 | |a The synthesis of ten new thyrotropin-releasing hormone analogues (15-24) which contain uncoded amino acids (L- and D-homoleucine, L- and D-homophenylalanine, L-homoproline and 6-ketopipecolic acid) is described here. The peptide bond formation was achieved in solution phase using pentafluorophenyl ester activation of the N-protected amino acids. The analogues were tested for their ability to release thyrotropin and for CNS activities and proved to be fully inactive. | |
| 650 | 4 | |a Klinikai orvostan | |
| 700 | 0 | 1 | |a Baláspiri L |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/31990/1/aok_klny_132_94.pdf |z Dokumentum-elérés |