N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins
Taking into account that multidrug resistance (MDR) is the main cause for chemotherapeutic failure in cancer treatment, the ability of novel histamine H3 receptor ligands to reverse the cancer MDR was evaluated, using the ABCB1 efflux pump inhibition assay in mouse MDR T-lymphoma cells. The most act...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2020
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| Sorozat: | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
30 No. 22 |
| Tárgyszavak: | |
| doi: | 10.1016/j.bmcl.2020.127522 |
| mtmt: | 31856961 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/28384 |