The Nuclear Localization Signal of NF-κB p50 Enters the Cells via Syndecan-Mediated Endocytosis and Inhibits NF-κB Activity
It is well established that cationic peptides can enter cells following attachment to polyanionic membrane components. We report that the basic nuclear localization signal (NLS) of the NF-κB p50 subunit is internalized via lipid raft-dependent endocytosis mediated by heparan sulfate proteoglycans an...
Elmentve itt :
Szerzők: |
Letoha Annamária Hudák Anett Bozsó Zsolt Vizler Csaba Veres Gábor Szilák László Letoha Tamás |
---|---|
Dokumentumtípus: | Cikk |
Megjelent: |
2023
|
Sorozat: | INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
29 No. 5 |
Tárgyszavak: | |
doi: | 10.1007/s10989-023-10548-9 |
mtmt: | 34050718 |
Online Access: | http://publicatio.bibl.u-szeged.hu/27832 |
Hasonló tételek
-
Lobatin b inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation
Szerző: Kiss Izabella, et al.
Megjelent: (2015) -
Cirsiliol Suppressed Epithelial to Mesenchymal Transition in B16F10 Malignant Melanoma Cells through Alteration of the PI3K/Akt/NF-κB Signaling Pathway
Szerző: Priyanka Prasad, et al.
Megjelent: (2019) -
Inhibition of COX-2 and NF-κB1 Gene Expression, NO Production, 5-LOX, and COX-1 and COX-2 Enzymes by Extracts and Constituents of Onopordum acanthium
Szerző: Lajter Ildikó, et al.
Megjelent: (2015) -
TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity
Szerző: Danis Judit, et al.
Megjelent: (2021) -
The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation
Szerző: Unger Christine, et al.
Megjelent: (2015)