Impact of the COVID-19 Pandemic on Ambulatory Care Antibiotic Use in Hungary A Population-Based Observational Study /

The COVID-19 pandemic and related restrictions have potentially impacted the use of antibiotics. We aimed to analyze the use of systemic antibiotics (J01) in ambulatory care in Hungary during two pandemic years, to compare it with pre-COVID levels (January 2015–December 2019), and to describe trends...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Hambalek Helga
Matuz Mária
Ruzsa Roxána
Engi Zsófia
Visnyovszki Ádám
Papfalvi Erika
Hajdú Edit
Doró Péter
Viola Réka
Soós Gyöngyvér
Csupor Dezső
Benkő Ria
Dokumentumtípus: Cikk
Megjelent: 2023
Sorozat:ANTIBIOTICS 12 No. 6
Tárgyszavak:
doi:10.3390/antibiotics12060970

mtmt:34045309
Online Access:http://publicatio.bibl.u-szeged.hu/27800
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520 3 |a The COVID-19 pandemic and related restrictions have potentially impacted the use of antibiotics. We aimed to analyze the use of systemic antibiotics (J01) in ambulatory care in Hungary during two pandemic years, to compare it with pre-COVID levels (January 2015–December 2019), and to describe trends based on monthly utilization. Our main findings were that during the studied COVID-19 pandemic period, compared to the pre-COVID level, an impressive 23.22% decrease in the use of systemic antibiotics was detected in ambulatory care. A significant reduction was shown in the use of several antibacterial subgroups, such as beta-lactam antibacterials, penicillins (J01C, −26.3%), and quinolones (J01M, −36.5%). The trends of antibiotic use moved in parallel with the introduction or revoking of restriction measures with a nadir in May 2020, which corresponded to a 55.46% decrease in use compared to the previous (pre-COVID) year’s monthly means. In general, the systemic antibiotic use (J01) was lower compared to the pre-COVID periods’ monthly means in almost every studied pandemic month, except for three months from September to November in 2021. The seasonal variation of antibiotic use also diminished. Active agent level analysis revealed an excessive use of azithromycin, even after evidence of ineffectiveness for COVID-19 emerged. 
650 4 |a Farmakológia és gyógyszerészet 
700 0 1 |a Matuz Mária  |e aut 
700 0 1 |a Ruzsa Roxána  |e aut 
700 0 1 |a Engi Zsófia  |e aut 
700 0 1 |a Visnyovszki Ádám  |e aut 
700 0 1 |a Papfalvi Erika  |e aut 
700 0 1 |a Hajdú Edit  |e aut 
700 0 1 |a Doró Péter  |e aut 
700 0 1 |a Viola Réka  |e aut 
700 0 1 |a Soós Gyöngyvér  |e aut 
700 0 1 |a Csupor Dezső  |e aut 
700 0 1 |a Benkő Ria  |e aut 
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