Subchronic exposure to methylmercury in male Wistar rats effects on neurobehavioral performance /
Humans are exposed to mercury by industrial emission, dental fillings, use of mercury-based fungicides and bactericides and via food. Mercury exposure results in altered behavioral, cognitive, coordinative and emotional functions of humans and animals. Cognitive behavior, open field activity and psy...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2002
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| Sorozat: | CENTRAL EUROPEAN JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
8 No. 2-3 |
| Tárgyszavak: | |
| mtmt: | 1294361 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/27658 |
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| 245 | 1 | 0 | |a Subchronic exposure to methylmercury in male Wistar rats |h [elektronikus dokumentum] : |b effects on neurobehavioral performance / |c Vezér Tünde |
| 260 | |c 2002 | ||
| 300 | |a 131-141 | ||
| 490 | 0 | |a CENTRAL EUROPEAN JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE |v 8 No. 2-3 | |
| 520 | 3 | |a Humans are exposed to mercury by industrial emission, dental fillings, use of mercury-based fungicides and bactericides and via food. Mercury exposure results in altered behavioral, cognitive, coordinative and emotional functions of humans and animals. Cognitive behavior, open field activity and psychomotor performance was studied in young adult male Wistar rats treated subchronically with methylmercury (II) chloride (0.5 and 2.0 mg/kg b.w.) per os by gavage. Spatial learning of the animals, investigated in a maze, was altered, demonstrated by lower performance in short-term, long-term and reference memory compared to the controls. Depending on the dose and the length of treatment, the number of animals making mistakes and the number of errors per animal was increasing. In the open field test, the treated rats showed decreased locomotor activity and diminished spontaneous exploratory activity. The changes seen in the methylmercury-treated rats were similar to those found in exposed humans which stresses the importance of monitoring and control of direct and indirect environmental exposure. | |
| 650 | 4 | |a Általános orvostudomány | |
| 700 | 0 | 1 | |a Papp András |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/27658/1/VezerT-metHg-behav.pdf |z Dokumentum-elérés |