Importance of extracardiac alpha(1)-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts
In anaesthetized rabbits, alpha(1)-adrenoceptor stimulation increases the propensity of repolarization-prolonging drugs to induce torsade de pointes ventricular tachycardia. However, it is not known whether the stimulation of intracardiac alpha(1)-adrenoceptors, or the increased ventricular stretch...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2006
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| Sorozat: | EUROPEAN JOURNAL OF PHARMACOLOGY
537 No. 1-3 |
| Tárgyszavak: | |
| doi: | 10.1016/j.ejphar.2006.03.014 |
| mtmt: | 1132573 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/22860 |