01681nab a2200253 i 4500 publ21133 20210331110420.0 210331s2020 hu o 0|| zxx d 2365-6549 10.1002/slct.202002093 doi 31625419 mtmt SZTE Publicatio Repozitórium hun zxx Pálinkás Noémi Synthesis of Axially Chiral Carboxamides via Aminocarbonylation of Aryl and Vinyl Iodides with 2,2'-Diamino-1,1'-binaphthalene in the Presence of Palladium Catalysts [elektronikus dokumentum] / Pálinkás Noémi 2020 11048-11051 CHEMISTRYSELECT 5 No. 35 Palladium-catalysed aminocarbonylation of iodobenzene and 1-iodocyclohexene with both enantiomerically pure and racemic 2,2'-diamino-1,1'-binaphthalene (BINAM) asN-nucleophile was carried out. The mono- and dicarboxamide enantiomers possessing axial chirality were synthesised using (S-ax)-BINAM. In the possession of these reference compounds the partial chiral kinetic resolution of racemic BINAM was carried out using various optically active bidentate ligands such as (2S,4S)-BDPP, (2S,3S)-CHIRAPHOS and (R)-BINAP. It was revealed by chiral HPLC measurements that up to 10 % enantiomeric excess of carboxamides can be achieved in this way. Although with low enantioselection, enantioselectve aminocarbonylation was carried out for the first time. Mikle Gábor aut Aranyi Anita aut Péter Antal aut Kollár László aut http://publicatio.bibl.u-szeged.hu/21133/1/Palinkas_Chemistry_Select_2020.pdf Dokumentum-elérés