Sarcopenia as an independent predictor of the surgical outcomes of patients with inflammatory bowel disease

Patients with inflammatory bowel disease (IBD) are at risk of sarcopenia, which is associated with poor clinical outcomes. We conducted this study to assess whether sarcopenia predicts the need for surgery and postoperative complications in patients with IBD. We performed a systematic search of four...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Erős Adrienn
Soós Alexandra
Hegyi Péter
Szakács Zsolt
Benke Márton
Szűcs Ákos
Hartmann Petra
Erőss Bálint Mihály
Sarlós Patrícia
Dokumentumtípus: Cikk
Megjelent: 2020
Sorozat:SURGERY TODAY 50
doi:10.1007/s00595-019-01893-8

mtmt:30850194
Online Access:http://publicatio.bibl.u-szeged.hu/19854
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520 3 |a Patients with inflammatory bowel disease (IBD) are at risk of sarcopenia, which is associated with poor clinical outcomes. We conducted this study to assess whether sarcopenia predicts the need for surgery and postoperative complications in patients with IBD. We performed a systematic search of four electronic databases, last updated in March, 2019. Data from studies comparing rates of surgery and postoperative complications in sarcopenic IBD patients versus non-sarcopenic IBD patients were pooled with the random-effects models. We calculated the odds ratios (OR) with a 95% confidence interval (CI). Ten studies with a collective total of 885 IBD patients were included in our meta-analysis. Although the analysis of raw data did not reveal significant differences between the two groups with respect to the rate of surgery and postoperative complications (OR = 1.826; 95% CI 0.913-3.654; p = 0.089 and OR = 3.265; 95% CI 0.575-18.557; p = 0.182, respectively), the analysis of adjusted data identified sarcopenia as an independent predictor for both of the undesirable outcomes (OR = 2.655; 95% CI 1.121-6.336; p = 0.027 and OR = 6.097; 95% CI 1.756-21.175; p = 0.004, respectively). Thus, early detection of sarcopenia in patients with IBD is important to prevent undesirable outcomes. 
700 0 1 |a Soós Alexandra  |e aut 
700 0 1 |a Hegyi Péter  |e aut 
700 0 1 |a Szakács Zsolt  |e aut 
700 0 1 |a Benke Márton  |e aut 
700 0 1 |a Szűcs Ákos  |e aut 
700 0 1 |a Hartmann Petra  |e aut 
700 0 1 |a Erőss Bálint Mihály  |e aut 
700 0 1 |a Sarlós Patrícia  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/19854/1/ErosSurgarytoday2020.pdf  |z Dokumentum-elérés