Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

One of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different in...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Lann, Le Lucas
Jouve Pierre-Emmanuel
Alarcón-Riquelme Marta
Jamin Christophe
PRECISESADS Flow Cytometry Study Group
PRECISESADS Clinical Consortium
Balog Attila
Bocskai Márta
Deák Magdolna
Dulic Sonja
Kádár Gabriella
Kovács László
Dokumentumtípus: Cikk
Megjelent: 2020
Sorozat:SCIENTIFIC REPORTS 10 No. 1
doi:10.1038/s41598-020-68468-3

mtmt:31390060
Online Access:http://publicatio.bibl.u-szeged.hu/19244
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520 3 |a One of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects. 
700 0 1 |a Jouve Pierre-Emmanuel  |e aut 
700 0 2 |a Alarcón-Riquelme Marta  |e aut 
700 0 2 |a Jamin Christophe  |e aut 
700 0 2 |a PRECISESADS Flow Cytometry Study Group  |e aut 
700 0 2 |a PRECISESADS Clinical Consortium  |e aut 
700 0 2 |a Balog Attila  |e aut 
700 0 2 |a Bocskai Márta  |e aut 
700 0 2 |a Deák Magdolna  |e aut 
700 0 2 |a Dulic Sonja  |e aut 
700 0 2 |a Kádár Gabriella  |e aut 
700 0 2 |a Kovács László  |e aut 
856 4 0 |u http://publicatio.bibl.u-szeged.hu/19244/1/LeLannSciReports2020.pdf  |z Dokumentum-elérés