High-dose phenylephrine increases meningeal blood flow through TRPV1 receptor activation and release of calcitonin gene-related peptide
Background The alpha(1)-adrenoceptor agonist, phenylephrine, is used at high concentrations as a mydriatic agent and for the treatment of nasal congestion. Among its adverse side-effects transient burning sensations are reported indicating activation of the trigeminal nociceptive system. Methods Neu...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2020
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| Sorozat: | EUROPEAN JOURNAL OF PAIN
24 No. 2 |
| doi: | 10.1002/ejp.1495 |
| mtmt: | 30956907 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/18874 |