The activation of PI 3-kinase/Akt pathway is involved in the acute effects of simvastatin against ischaemia and reperfusion-induced arrhythmias in anaesthetised dogs

The activation of PI 3-kinase/Akt pathway is involved in the acute effects of simvastatin against ischaemia and reperfusion-induced arrhythmias in anaesthetised dogs

The objective of this study was to examine whether the PI3-kinase/Akt pathway is involved in the activation of endothelial nitric oxide synthase (eNOS) and in the subsequent increase of nitric oxide (NO) production that has been proved to play a role in the antiarrhythmic effect of acute simvastatin...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Kisvári Gábor
Kovács Mária
Seprényi György
Végh Ágnes
Dokumentumtípus: Cikk
Megjelent: 2015
Sorozat:EUROPEAN JOURNAL OF PHARMACOLOGY 769
doi:10.1016/j.ejphar.1015.11.016

mtmt:3032033
Online Access:http://publicatio.bibl.u-szeged.hu/17400

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