2-Iodo-4 '-Methoxychalcone Attenuates Methylglyoxal-Induced Neurotoxicity by Activation of GLP-1 Receptor and Enhancement of Neurotrophic Signal, Antioxidant Defense and Glyoxalase Pathway
Methylglyoxal (MG) acts as a reactive precursor of advanced glycation end products (AGEs). This compound is often connected with pathologies such as diabetes, neurodegenerative processes and diseases of aging. 2-iodo-4 '-methoxychalcone (CHA79), a synthetic halogen-containing chalcone derivativ...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2019
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| Sorozat: | MOLECULES
24 No. 12 |
| doi: | 10.3390/molecules24122249 |
| mtmt: | 30759845 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/16702 |