Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG/KCNH2 proteins in the heart
Reduced levels of hERG protein and the corresponding repolarizing current IKr can cause arrhythmia and sudden cardiac death, but the underlying cellular mechanisms controlling hERG surface expression are not well understood. We identified TRIOBP-1, an F-actin binding protein previously associated wi...
Elmentve itt :
| Szerzők: | |
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2018
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| Sorozat: | JOURNAL OF CELL SCIENCE
131 No. 6 |
| doi: | 10.1242/jcs.206730 |
| mtmt: | 3346396 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/16235 |