Synthesis and multidrug resistance reversal activity of 1,2-disubstituted tetrahydroisoquinoline derivatives
Background: Cancer treatment often fails due to multidrug resistance (MDR) of the tumor cells. One of the major causes is overexpression of P-glycoprotein (P-gp). Materials and Methods: By N-substitution reactions of diamine, amino acid and amino alcohol derivatives with 1-substituted tetrahydroisoq...
Elmentve itt :
| Szerzők: | |
|---|---|
| Dokumentumtípus: | Cikk |
| Megjelent: |
2004
|
| Sorozat: | ANTICANCER RESEARCH
24 No. 3A |
| mtmt: | 1013245 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/16161 |