Sustainable synthesis of N-methylated peptides in a continuous-flow fixed bed reactor
A rapid, simplified and highly efficient continuous-flow solid-phase peptide synthesis technology is reported for the direct synthesis of mono and multiple N-methylated cyclic alanine and valine peptides. Through an optimization study, we find that only 1.5 equivalents of the amino acids are suffici...
Elmentve itt :
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| Dokumentumtípus: | Cikk |
| Megjelent: |
2018
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| Sorozat: | JOURNAL OF FLOW CHEMISTRY
8 No. 1 |
| doi: | 10.1007/s41981-018-0002-9 |
| mtmt: | 3374072 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/14629 |