Building β-peptide H10/12 foldamer helices with six-membered cyclic side-chains fine-tuning of folding and self-assembly /
The ability of the beta-peptidic H10/12 helix to tolerate side-chains containing six-membered alicyclic rings was studied. cis-2-Aminocyclohex-3-ene carboxylic acid (cis-ACHEC) res dues afforded H10/12 helix formation with alternating backbone configuration. Conformational polymorphism was observed...
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| Dokumentumtípus: | Cikk |
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American Chemical Society
2010
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| Sorozat: | ORGANIC LETTERS
12 No. 23 |
| doi: | 10.1021/ol102494m |
| mtmt: | 1412123 |
| Online Access: | http://publicatio.bibl.u-szeged.hu/11877 |
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| 005 | 20200225094116.0 | ||
| 008 | 170831s2010 hu o 0|| zxx d | ||
| 022 | |a 1523-7060 | ||
| 024 | 7 | |a 10.1021/ol102494m |2 doi | |
| 024 | 7 | |a 1412123 |2 mtmt | |
| 040 | |a SZTE Publicatio Repozitórium |b hun | ||
| 041 | |a zxx | ||
| 100 | 1 | |a Mándity István M. | |
| 245 | 1 | 0 | |a Building β-peptide H10/12 foldamer helices with six-membered cyclic side-chains |h [elektronikus dokumentum] : |b fine-tuning of folding and self-assembly / |c Mándity István M. |
| 260 | |a American Chemical Society |c 2010 | ||
| 300 | |a 5584-5587 | ||
| 490 | 0 | |a ORGANIC LETTERS |v 12 No. 23 | |
| 520 | 3 | |a The ability of the beta-peptidic H10/12 helix to tolerate side-chains containing six-membered alicyclic rings was studied. cis-2-Aminocyclohex-3-ene carboxylic acid (cis-ACHEC) res dues afforded H10/12 helix formation with alternating backbone configuration. Conformational polymorphism was observed for the alternating cis-ACHC hexamer, where chemical exchange takes place between the major left-handed H10/12 helix and a minor folded conformation. The hydrophobically driven self-assembly was achieved for the cis-ACHC-containing helix which was observed as vesicles similar to 100 nm in diameter. | |
| 700 | 0 | 1 | |a Fülöp Lívia |e aut |
| 700 | 0 | 1 | |a Vass Elemér |e aut |
| 700 | 0 | 1 | |a Tóth Gábor |e aut |
| 700 | 0 | 1 | |a Martinek Tamás A. |e aut |
| 700 | 0 | 1 | |a Fülöp Ferenc |e aut |
| 856 | 4 | 0 | |u http://publicatio.bibl.u-szeged.hu/11877/1/mandity2010.pdf |z Dokumentum-elérés |