Ubiquitylation-mediated RNAPII genomic eviction in response to DNA DSBs
Essential biological functions are constantly challenged by genotoxic stresses. During transcription, DNA Damage can occur at any stage predisposing genomic stability through the direct damage to DNA and formation of aberrant/truncated transcripts. A central surveillance mechanism is operated by R...
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| Dokumentumtípus: | Disszertáció |
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2024-11-22
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| Online Access: | http://doktori.ek.szte.hu/12363 |