01682naa a2200265 i 4500 acta82376 20231122093728.0 231122s2023 hu o 1|| eng d 978-963-306-963-9 SZTE Egyetemi Kiadványok Repozitórium hun eng Biricioiu Roxana Glycolipidomics of human cerebellum in development and aging by ion mobility tandem mass spectrometry [elektronikus dokumentum] / Biricioiu Roxana University of Szeged Szeged 2023 95-96 Proceedings of the International Symposium on Analytical and Environmental Problems 29 In this study ion mobility separation (IMS) mass spectrometry (MS) was for the first time introduced in human cerebellum ganglioside research. The work was focused on a comprehensive mapping and structural characterization of human cerebellar gangliosides and determination of the specific changes induced in their expression by brain development and aging. We have carried out a comparative IMS MS mapping of the native ganglioside mixtures extracted from fetal cerebellum in the second trimester of pregnancy vs. near-term fetus vs. aged cerebellum, followed by IMS CID MS/MS fragmentation analysis. Természettudományok Kémiai tudományok Tömegspektrometria Sarbu Mirela aut Ica Raluca aut Zamfir Alina D. aut 29th International Symposium on Analytical and Environmental Problems Szeged 2023. november 13-14. http://acta.bibl.u-szeged.hu/82376/1/proceedings_of_isaep_2023_095-096.pdf Dokumentum-elérés