Experimental study of the interaction of one local anesthetic with a cellulose type support

The extent of the adsorption of a local anesthetic (Bupivacaine) on a pharmaceutical adsorbent, namely microcrystalline cellulose (MCC) suspended in aqueous solution was investigated spectrophotometrically at three different temperatures. The equilibrium adsorption contact times were determined for...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerzők: Simu Georgeta-Maria
Muntean Simona Gabriela
Grad Maria
Testületi szerző: International Symposium on Analytical and Environmental Problems (17.) (2011) (Szeged)
Dokumentumtípus: Könyv része
Megjelent: SZAB Szeged 2012
Sorozat:Proceedings of the International Symposium on Analytical and Environmental Problems 17
Kulcsszavak:Gyógyszerkémia
Tárgyszavak:
Online Access:http://acta.bibl.u-szeged.hu/76462
Leíró adatok
Tartalmi kivonat:The extent of the adsorption of a local anesthetic (Bupivacaine) on a pharmaceutical adsorbent, namely microcrystalline cellulose (MCC) suspended in aqueous solution was investigated spectrophotometrically at three different temperatures. The equilibrium adsorption contact times were determined for all the temperatures and were found around 90 minutes. Adsorption isotherms have been analyzed by the Freundlich and Langmuir models. The obtained results indicated that the Freundlich isotherms presented the highest correlation coefficients, and thus they describe better the adsorption of the studied drug on MCC.
Terjedelem/Fizikai jellemzők:355-358
ISBN:978-963-315-066-5