02723nab a2200409 i 4500 acta73060 20230227150042.0 210715s2020 hu o 0|| eng d 1588-4082 10.14232/abs.2020.2.99-109 doi SZTE Egyetemi Kiadványok Repozitórium hun eng Váradi Orsolya A. Lipid biomarker-based verification of TB infection in mother’s and daughter’s mummified human remains (Vác Mummy Collection, 18th century, CE, Hungary) [elektronikus dokumentum] / Váradi Orsolya A. 2020 99-109 Acta biologica Szegediensis 64 No. 2 The perpetual burden of tuberculosis (TB) keeps drawing the focus of research on this disease. Among other risk factors (e.g., poor living conditions, malnutrition, smoking, HIV infection, etc.), being in close contact with a TB infected person requires special attention. For a better understanding of the disease, paleopathological investigations concerning TB have been carried out with various techniques for a long a time; nevertheless, analysis of incidence among family members is hardly possible in past populations. An exceptional group of naturally mummifi ed individuals, the collection of the Vác mummies (Hungary, 18th century CE), is known about the large TB incidence rate, which has been revealed by aDNA analysis. Besides the high rate of TB infection, another interesting aspect of the collection is that in some cases, the family connections could be reconstructed. In this paper, we present the mycocerosic acid profi les gained by HPLC-HESI-MS measurements of two Vác mummies, who were mother and daughter according to the personal records. Earlier metagenomic analysis already revealed mixed M. tuberculosis infection with the same bacterial strains in both individuals; moreover, the same bacterial strains were recorded in both cases. Orvos- és egészségtudomány Egészségtudományok Egyéb orvostudományok Múmia, Embertan, Paleopatológia, Tuberkulózis Szikossy Ildikó aut Spekker Olga aut Rakk Dávid aut Terhes Gabriella aut Urbán Edit aut Berthon William aut Pap Ildikó aut Maixner Frank aut Zink Albert aut Vágvölgyi Csaba aut Donoghue Helen D. aut Minnikin David E. aut Pálfi György aut Szekeres András aut http://acta.bibl.u-szeged.hu/73060/1/biologica_064_numb_002_099-109.pdf Dokumentum-elérés