Effects of ethanol on the hepatic DNA in materno-fetal complex and on the serum proteins in pregnant female rats
Experimental investigations on the action of ethanol were performed on pregnant female rats and their fetuses. The Wistar strain pregnant rats were included into an experimental (E) and a control (C) group. Animals of experimental group received ethanol and thecontrol group consumed tap water. At th...
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| Dokumentumtípus: | Könyv része |
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2019
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| Sorozat: | Proceedings of the International Symposium on Analytical and Environmental Problems
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| Kulcsszavak: | Biokémia |
| Online Access: | http://acta.bibl.u-szeged.hu/64804 |
| Tartalmi kivonat: | Experimental investigations on the action of ethanol were performed on pregnant female rats and their fetuses. The Wistar strain pregnant rats were included into an experimental (E) and a control (C) group. Animals of experimental group received ethanol and thecontrol group consumed tap water. At the end of the experiment blood samples and liver samples were taken for analysis. In the present study there were pursued values of some biochemical parameters, i.e. maternal and fetal hepatic DNA concentration, maternal serumproteins and electrophoretic fractions (albumins as well as α-, β- and γ-globulins). The obtained data revealed a statistically non-signifiant increase of hepatic DNA both in mothers and fetuses of experimental group. Serumproteins concentration in the pregnant rats showed a significant increase. Regarding the electrophoretic fractions, a decrease of albumins and increase of globulins were observed . As to globulin subfractions a hyper-α-globulinemia, hypo-β- and hypo-γ-globulinemia were revealed. |
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| Terjedelem/Fizikai jellemzők: | 137-140 |
| ISBN: | 978-963-306-702-4 |