Experimental study of the ibuprofene’s interaction with some natural supports

The interaction of ibuprofene with two natural solid supports (orange peel and cotton fibre) was studied at three different temperatures (25, 35 and 45 oC) aiming to establish the best theoretical adsorption model and the corresponding thermodynamic parameters (enthalpy and entropy) of the process....

Full description

Saved in:
Bibliographic Details
Main Authors: Simu Georgeta-Maria
Grad Maria
Fessi Sabrine
Corporate Author: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Format: Book part
Published: 2015
Series:Proceedings of the International Symposium on Analytical and Environmental Problems 21
Kulcsszavak:Analitikai kémia, Adszorpció
Online Access:http://acta.bibl.u-szeged.hu/55983
Description
Summary:The interaction of ibuprofene with two natural solid supports (orange peel and cotton fibre) was studied at three different temperatures (25, 35 and 45 oC) aiming to establish the best theoretical adsorption model and the corresponding thermodynamic parameters (enthalpy and entropy) of the process. For the investigated systems, the time necessary for attaining the adsorption equilibrium was estimated through a series of preliminary experiments, which indicated periods of time ranging from 195 to 380 minutes. Further, the experimental data resulted from the adsorption process was fitted to the Freundlich and Langmuir classical adsorption models, but also to the Sips and Jossens isotherm models, which were not tested yet in the case of the present studied systems. The obtained results showed that for both investigated systems it was the Sips model which described better the interaction of the model drug with the investigated solid supports.
Physical Description:282-286
ISBN:978-963-306-411-5