Retention and lipophilicity of newly synthesized 3-benzyloxy steroid derivatives in normal- and reversed-phase HPLC

The retention behaviour and separation ability of nine newly synthesized 3-benzyloxy estrone derivatives were studied by FIPLC on silica and C-18 commercially available columns. The mobile phases used were: benzene-ethyl acetate, benzene-tetrahydrofuran, benzene-acetonitrile, methanolwaler and aceto...

Teljes leírás

Elmentve itt :
Bibliográfiai részletek
Szerző: Ačanski Marijana M.
Dokumentumtípus: Cikk
Megjelent: 2012
Sorozat:Review of faculty of engineering : analecta technica Szegedinensia
Kulcsszavak:Mérnöki tudományok, Kémia
Online Access:http://acta.bibl.u-szeged.hu/11909
Leíró adatok
Tartalmi kivonat:The retention behaviour and separation ability of nine newly synthesized 3-benzyloxy estrone derivatives were studied by FIPLC on silica and C-18 commercially available columns. The mobile phases used were: benzene-ethyl acetate, benzene-tetrahydrofuran, benzene-acetonitrile, methanolwaler and acetonitrilc-water in various proportions. The results are discussed in terms of nature of the solute, eluent and stationary phase. The correlation between the retention constants of nine 3- benzyloxy estrone derivatives obtained on C-18 column and calculated log P was examined too.
Terjedelem/Fizikai jellemzők:6-15
ISSN:1788-6392